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When the HLF (hepatic leukemia factor) gene -- which is expressed in immature blood cells -- does not shut down on time, we are unable to develop a functional long-term immune system, investigators have found. This could be a very…
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The environment surrounding a tumor can trigger metastatic behavior in cancer cells, a team of bioengineers and bioinformaticians has discovered. Specifically, when tumor cells are confined in a dense environment, the researchers found that they turn on a specific set…
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In pursuit of a better imaging phantom for improved tumor measurements, scientists hit upon an effective but unconventional solution: injecting water into disposable diapers.
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Scientists have engineered a mouse model to study a rare and often-fatal form of liver cancer. They've used it to clarify what drives these tumors at the molecular level, and discover new drug concepts.
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A new nanomapping technology could transform the way disease-causing genetic mutations are diagnosed and discovered.
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Cancer researchers seeking non-toxic alternatives to harmful chemotherapy are reporting a highly significant result for a humble cold remedy.
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A significant proportion of children and young adults with treatment-resistant B-cell leukemia who participated in a small study achieved remission with the help of a new form of gene therapy, according to researchers.
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Researchers have found a way to boost the cancer-destroying ability of the immune system's T-cells, offering new hope in the fight against a wide range of cancers.
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Osimertinib improves progression-free survival compared to standard first line therapy in Asian patients with EGFR-mutated non-small-cell lung cancer (NSCLC), according to the Asian subset analysis of the FLAURA trial.
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A recent study showed approximately one-fifth of patients with cancer experienced post-traumatic stress disorder (PTSD) several months after diagnosis, and many of these patients continued to live with PTSD years later.
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Researchers can use a new type of measurement to predict how drugs will affect cancer cells taken from multiple myeloma patients. Their predictions correlated with how those patients actually fared when treated with those drugs.
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Drugs designed to halt cancer growth may offer a new way to control high blood pressure (hypertension), say investigators. The finding could offer a real advance in hypertension treatment because although a number of high blood pressure drugs are now…
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Women with higher body mass index (BMI) face an increased risk of not detecting their breast tumor until it has become large, according to a new study. Researchers said the findings suggest that women with higher BMI may need shorter…
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The immune cells that are trained to fight off the body's invaders can become defective. It's what allows cancer to develop. So most research has targeted these co-called effector T-cells. But a new study takes a step back and considers:…
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Scientists have made a discovery that could reduce the spread of cancer by hindering a protein that binds cancer cells together and allows them to invade tissues. The groundbreaking study identified a protein, known as cadherin-22, as a potential factor…
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A new study has shown that the majority of people in the United Kingdom do not understand the connection between weight issues and cancer. Obesity is associated with thirteen types of cancer, including those of the breast, kidney, bowel, and…
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A new protein has been identified in a common subtype of breast cancer which can potentially offer more effective therapies for the future.
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Researchers have developed a computer program to find new indications for old drugs. The computer program, called DrugPredict, matches existing data about FDA-approved drugs to diseases, and predicts potential drug efficacy. In a recent study, the researchers successfully translated DrugPredict…
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Researchers are developing a new tool for liquid biopsy that can detect RNA biomarkers from cancer cells in a patient's blood much more accurately and completely than other existing methods. This could soon provide doctors with a more complete picture…
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A discovery might help designers of miniature 'lab-on-a-chip' technologies to grow three-dimensional colonies of cancer cells inside a chip's tiny chambers, rather than the merely two-dimensional colonies that they generally can culture now. Chips with 3-D cell arrays could furnish…
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