Solange Peters, MD, PhD from the University of Lausanne, Lausanne, Switzerland discusses some of the open questions that surround targeted therapy and immunotherapy in patients with lung cancer. The major question that is currently being discussed is whether immunotherapy should be given to patients where there is a significantly reduced response and, whether certain therapies should be given to never-smokers. This interview was recorded at the annual meeting of European Lung Cancer Conference (ELCC) 20171 in Geneva, Switzerland.