S. P. Somashekhar, MCh, FRCS.Ed, from the Manipal Comprehensive Cancer Center, India, talks to us about the use of the IBM Watson for Oncology (WFO) cognitive computing system for lung and colorectal cancer treatment and its potential as a companion to physicians in helping to identify the best treatment regimen for cancer patients whilst avoiding the need for trial-and-error. This interview was filmed at the American Society of Oncology (ASCO) 2017 Annual Meeting in Chicago, IL.