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NCRI 2016 | Perspective on immune modulation to fight cancer

Lieping Chen, MD, PhD of Yale School of Medicine, New Haven, CT discusses two approaches to cancer immunotherapy. Immune system activation approach aims to push the immune system to the limit, but this may result in toxicities before treatment efficacy is reached. The alternative approach, as shown in the PD-1/PD-L1 study, is to regulate the immune system response to the normal level, which offers lower toxicity levels compared to other treatments like chemotherapy. Recorded at the 2016 National Cancer Research Institute (NCRI) Conference in Liverpool, UK.