Liza Villaruz, MD, University of Pittsburgh, Pittsburgh, PA, describes strategies to improve outcomes in metastatic non-small cell lung cancer (NSCLC). Whilst targeted therapies have had a profound effect on the treatment landscape, demographic disparities in next generation sequencing (NGS) remain a hurdle. By providing equitable care, patient outcomes can be optimized by receiving therapies that target relevant oncogenic drivers. This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL