In this podcast, we bring you the latest insights into managing brain metastases, with expert commentary from Minesh Mehta, MD, Miami Cancer Institute, Miami, FL; Sunandana Chandra, MD, MS, Northwestern University, Chicago, IL; Gaia Griguolo, MD, University of Padova, Padova, Italy; Orit Kaidar-Person, MD, Sheba Medical Center, Ramat Gan, Israel; and Janice Wing-Hang Tsang, MBBS, MRCP, FRCP, University of Hong Kong, Hong Kong, China,.

We will cover key findings from the Phase III METIS trial (NCT02831959), which explored Tumor Treating Fields (TTFields) therapy in patients with non-small cell lung cancer and brain metastases. Other topics include the complexities of managing symptomatic brain metastases in melanoma, new advances in breast cancer treatment with anti-HER2 agents, and the role of radiotherapy in preserving cognitive function. Finally, we’ll discuss data from the DESTINY-Breast01, -02, and -03 trials (NCT03248492, NCT03523585, NCT03529110) on the CNS efficacy of trastuzumab deruxtecan (T-DXd).

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