Yeah, so I hope that we see more of these kinds of studies over the forthcoming years. I think we have got a much more in-depth understanding over the last decade of how clonal involution impacts patient outcomes, just in terms of prognosis and in response to treatments. By linking it to spatial biology and histological patterns, that’s a mechanism of translating it into the clinic. And I think that we need more studies to try and find those links between genetic evolutionary factors and tissue morphology in order to try and get these concepts in a scalable way in the clinical setting...
Yeah, so I hope that we see more of these kinds of studies over the forthcoming years. I think we have got a much more in-depth understanding over the last decade of how clonal involution impacts patient outcomes, just in terms of prognosis and in response to treatments. By linking it to spatial biology and histological patterns, that’s a mechanism of translating it into the clinic. And I think that we need more studies to try and find those links between genetic evolutionary factors and tissue morphology in order to try and get these concepts in a scalable way in the clinical setting.
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