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BTOG 2026 | How can early radiotherapy benefit patients with lung cancer?
Matthew Hatton, MBChB, MSc, FRCP, FRCR, University of Sheffield, Sheffield, UK, comments on the use of radiotherapy in patients with bulky thoracic disease, where systemic treatments often struggle to control the disease, and relapse is likely to occur in the thoracic region. Early radiotherapy can be beneficial in preventing or delaying relapse, improving quality of life, and enhancing patient outcomes, utilizing modern radiotherapy techniques such as conformal therapy and high-dose fractionations. This interview took place at the 2026 British Thoracic Oncology Group (BTOG) congress in Edinburgh, UK.
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Transcript
So I think what we’re about with these trials is very much looking at those patients who have bulky thoracic disease. It’s difficult to control even with the best of systemic treatments and it is likely that when they relapse that’s where they’ll relapse. So the hope is that by giving radiotherapy early, you’re preventing or delaying relapse, you’re improving quality of life and improving patient outcomes...
So I think what we’re about with these trials is very much looking at those patients who have bulky thoracic disease. It’s difficult to control even with the best of systemic treatments and it is likely that when they relapse that’s where they’ll relapse. So the hope is that by giving radiotherapy early, you’re preventing or delaying relapse, you’re improving quality of life and improving patient outcomes. To do that, obviously, we’re using now up-to-date radiotherapy techniques. So conformal therapy for certain tumors. We’re looking at high-dose fractionations and using whatever radiotherapy technology centers have available for them. And a similar thing in quartz lung should be quiet lung or more likely quart or more accurately quart is not correct it should be quiet: those were using low-dose radiotherapy treatments or palliative radiotherapy to try and just, say, sort of keep symptoms at bay.
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