Yeah, we have presented the results of our systematic review where we address the question whether narrow margins are necessary to improve the outcomes of melanoma surgery because currently there is no prospective evidence that a second wide local excision is necessary in the management of this malignancy. We have tried to project our systematic review regarding all the different histological subtypes...
Yeah, we have presented the results of our systematic review where we address the question whether narrow margins are necessary to improve the outcomes of melanoma surgery because currently there is no prospective evidence that a second wide local excision is necessary in the management of this malignancy. We have tried to project our systematic review regarding all the different histological subtypes. We have found that for example in acral melanoma as well as in superficial spreading melanoma or nodular melanoma, there are no significant differences regarding local recurrence or melanoma-specific survival when comparing narrower margins than what the guidelines recommend. This is obviously really important because, for example, in acral melanomas, doing a smaller excision and not going down to certain structures such as the fascia allows for a better functional recovery and a better cosmetic outcome. I think it’s of utmost importance. I think we should start to personalize our approach to whether we have to do this second surgery. Right now we are only focusing on the Breslow index and that’s the only thing that matters to say how narrow the excision has to be and I think that we have to take into account, as I said, the cosmetic outcomes, the functional outcomes, the localization, and probably another histopathological variables like, for example, the histological subtype.
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