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iwCAR-T 2022
28 Apr–01 May 2022 | Tampa, FL / Online
The 4th International Workshop on CAR-T (iwCAR-T) took place on 28 April – 1 May 2022 in Tampa, FL, with VJHemOnc & VJOncology as official media partners. The workshop is a high-level discussion forum for research leaders in the field of CAR-T to share their perspectives on how to place this evolving understanding in a clinical context and thereby optimize clinical care. This year, a full day was dedicated to CAR-T therapy for solid cancers.
Session I: Emerging CARs and future challenges in solid tumors
Clinical perspective IO/TILs to BiTEs to TCR to CARs
Julian Molina Mayo Clinic, Rochester, MN, Rochester, MN, United States
anti-HER2 CAR macrophages in solid tumors
Kim Reiss Binder University of Pennsylvania, Philadelphia, PA, Philadelphia, PA, United States
Human iPSC-derived CAR-Ts with T-cell anti-tumor activity
Daniel Wang City of Hope, Duarte, CA, Duarte, CA, United States
Session 2: GU cancers
PSMA-redirected Armored CAR-Ts for mCRPC
Vivek Narayan University of Pennsylvania, Philadelphia, PA, Philadelphia, PA, United States
Armored CAR-T therapy in mPC
Joseph Fraietta University of Pennsylvania, Philadelphia, PA, Philadelphia, PA, United States
P-PSMA-101 CAR-Ts for mCRPC
Susan Slovin Memorial Sloan Kettering Cancer Center, New York, NY, New York City, NY, Afghanistan
MAGE-A4 TCR for solid tumors
David Hong The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Session 3: CAR-T clinical advances in solid tumors – lung
Landscape overview
Sandip Patel UC San Diego Health, San Diego, CA, San Diego, CA, United States
TILs treatment for lung cancer
Sylvia Lee Fred Hutchinson Cancer Research Center, Seattle, WA, Seattle, WA, United States
Overcoming barriers to CAR-T therapy in solid tumors
Shivani Srivastava Fred Hutchinson Cancer Research Center, Seattle, WA, Houston, TX, United States
‘Off-the-shelf’ PRBCs and iNKT cells
Melissa Johnson Sarah Cannon Research Institute, Nashville, TN
Session 4: Breast and ovarian cancers
CER T-cell technology for ovarian cancer
Jose Conejo-Garcia H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, Tampa, FL, United States
BNT211: CLDN6 CAR-Ts & CARVac-based CAR-T in vivo expansion
Winfried Alsdorf University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Hamburg, Germany
Session 5: GI cancers
I-O to cell therapy; IO/T-VEC, BiTEs/TCRs
Joel Randolph Hecht UCLA Health, Los Angeles, Los Angeles, CA, United States
Precision Promise: an adaptive phase 2/3 platform for drug development
Diane Simeone NYU Langone Health, New York City, NY, New York City, NY, United States
HuCART-meso cells in patients with pancreatic cancer
Mark O'Hara University of Pennsylvania, Philadelphia, PA, Philadelphia, PA, United States
The future of logic-gated cell therapy
William Go A2 Biotherapeutics, Agoura Hills, CA, Agoura Hills, CA, United States
Session 6: Head/neck and CNS cancers
Cellular immunotherapy in head and neck cancers
Kedar Kirtane H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
Session 7: Melanoma, sarcomas
TILs for metastatic melanoma
Sylvia Lee Fred Hutchinson Cancer Research Center, Seattle, WA, Seattle, WA, United States
The 4th International Workshop on CAR-T has been supported by:
