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iwCAR-T 2025

The 7th International Workshop on CAR-T and Bispecifics (iwCAR-T)
11–13 April 2025 | Miami, FL

iwCAR-T 2025

The 7th International Workshop on CAR-T and Bispecifics (iwCAR-T)
11–13 April 2025 | Miami, FL
The 7th International Workshop on CAR-T and Bispecifics (iwCAR-T)  took place in Miami, FL, on April 11-13, 2025, bringing together leading clinical researchers to discuss the latest advances in CAR therapies and bispecific antibodies.
The iwCAR-T and bispecifics 2025 Workshop was supported by Genetech, Johnson & Johnson, Kite, Bristol Myers Squibb, A2 BIO, Galápagos, Miltenyi Biomedicine, Caribou Biosciences, nkarta, Novartis, Legend Biotech, Immatics, Autolus, Biontech and Iovance biotherapeutics. Supporters have no influence over the production of content.

Keynote lecture

Prasad Adusumilli
How solid CAR-T targeting has evolved
Prasad Adusumilli Memorial Sloan Kettering Cancer Center, New York City, NY, United States

CARs targeting cell surface proteins (part I)

Michael  Gormally
DLL3-CAR-T for SCLC
Michael Gormally Memorial Sloan Kettering Cancer Center, New York City, NY, United States
Benjamin Schlechter
GCC19 CAR-T therapy for refractory colorectal cancer: Overcoming challenges in expansion and persistence
Benjamin Schlechter Dana-Farber Cancer Institute, Boston, MA, United States
Joel Randolph Hecht
Updates on logic-gated CAR T-cell therapies in pancreatic cancer
Joel Randolph Hecht UCLA Health, Los Angeles, CA, United States
Jennifer Specht
An update on CAR T-cell therapy for breast and ovarian cancer: A long and winding road
Jennifer Specht University of Washington, Seattle, WA, United States

CARs targeting cell surface proteins (part II)

Winfried Alsdorf
CLDN6-targeted therapy with CAR T-cells +/- CARVac in relapsed germ cell tumors
Winfried Alsdorf University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Susanne Baumeister
hALK.CAR T-cells for relapsed/refractory neuroblastoma
Susanne Baumeister Dana-Farber Cancer Institute, Boston, MA, United States
Monica  Avila
Cell therapy advances in ovarian cancer: What we know and where we’re headed
Monica Avila Moffitt Cancer Center, Tampa, FL, United States

T-cell engagers and TCRs

Mihaela Druta
Afami-Cel in metastatic synovial sarcoma: The 1st genetically engineered TCR therapy approved for a solid tumor
Mihaela Druta H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
Michael  Gormally
Immunologic targeting of undruggable TP53 hotspot mutations through T-cell receptor gene therapy
Michael Gormally Memorial Sloan Kettering Cancer Center, New York City, NY, United States
Jason Luke
Targeting PRAME with TCR T-cells first in melanoma then beyond
Jason Luke University of Pittsburgh, Pittsburgh, PA, PA, United States

TILs across solid tumors

Ben Creelan
Promising T-cell targets in lung cancers: Trial updates
Ben Creelan Moffitt Cancer Center, Tampa, FL, United States
Coming soon
Michael Poch
TIL therapy for GU malignancies
Michael Poch Moffitt Cancer Center, Tampa, FL, United States
Coming soon
Allison Betof Warner
Optimizing TIL therapy for melanoma & beyond
Allison Betof Warner Stanford Medicine, Stanford, CA, United States
Coming soon

Novel technologies in solid tumors

Marco  Davila
Genome-edited anti-GPC3 CAR for hepatoma
Marco Davila Roswell Park Comprehensive Cancer Center, Buffalo, NY, United States
Coming soon
Saar Gill
CAR-M: Engineering myeloid cells for solid tumor immunotherapy
Saar Gill University of Pennsylvania, Philadelphia, PA, United States
Coming soon
Saul Priceman
Advancing T-cell therapies for solid cancers
Saul Priceman Keck School of Medicine of USC, Los Angeles, CA, United States
Coming soon