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How does a normal cell turn into a deadly cancer? Seeking an answer to this Question researchers examined the tumor genomes of nearly 300 prostate cancer patients. Their findings describe the ways in which changes in the prostate cells' genetic…
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Researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia (ALL) patients.
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Exercise has been touted to build bone mass, but exactly how it actually accomplishes this is a matter of debate. Now, researchers show that an exercise-induced hormone activates cells that are critical for bone remodeling in mice. A study identifies…
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No drugs are currently available to treat Ebola, Dengue, or Zika viruses, which infect millions of people every year and result in severe illness, birth defects, and even death. Scientists may finally change that. They identified key ways the three…
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Excess body weight accounted for approximately 3.9 percent of all cancers worldwide in 2012, a figure that is expected to rise in the coming decades given current trends.
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Researchers have made a significant breakthrough by developing the 3D structure of proteins from inside the eye lens that control how cells communicate with each other, which could open the door to treating diseases such as cataracts, stroke and cancer.
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Pseudoachondroplasia (PSACH) is a severe inherited dwarfing condition In PSACH, a genetic mutation leads to abnormal retention of cartilage oligomeric matrix protein (COMP) within the endoplasmic reticulum (ER) of cartilage-producing cells (chondrocytes), which interferes with function and cell viability. Investigators…
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A report describes a new assay to assess copy number alterations that is cheaper, faster, reproducible, and requires less tissue than other diagnostic techniques and has the potential to significantly enhance prostate cancer evaluation.
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A novel technique that uses mammography to determine the biological tissue composition of a tumor could help reduce unnecessary breast biopsies, according to a new study.
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Scientists report a time-keeping mechanism in liver cells that helps sustain key organ tasks can contribute to diseases when its natural rhythm is disrupted.
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A new computational model gives a clearer picture of the structure and mechanics of soft, shape-changing cells that could provide a better understanding of cancerous tumor growth, wound healing, and embryonic development.
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A widely used diabetes medication combined with an antihypertensive drug specifically inhibits tumor growth - this was discovered by researchers two years ago. In a follow-up study, scientists report that this drug cocktail induces cancer cell death by switching off…
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An analysis of nearly 20,000 cancer patient histories and genetic data has revealed that knowing the genetic cause of a cancer does not help predict how deadly the disease will be. Instead, researchers have discovered that copy number variations in…
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Scientists have developed a new technique that uses light to understand how cells communicate in human disease.
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A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, researchers report.
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The increased risk for breast cancer that occurs after childbirth can last more than 20 years. The risk may be enhanced when a woman is older at first birth or has a family history of breast cancer, and is not…
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A research team has developed a spray gel embedded with immune-boosting drugs that could help lower the risk of cancer recurrence after surgery.
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A new study suggests that a slow-growing brain tumor arising in patients affected by neurofibromatosis type 1 (NF1) may be vulnerable to immunotherapy, which gives the immune system a boost in fighting cancer.
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A physicist hopes to improve cancer detection with a new and novel class of nanomaterials.
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An international team of researchers has developed, calibrated, and validated a novel tool for identifying the genetic changes in Lynch syndrome genes that are likely to be responsible for causing symptoms of the disease.
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