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The results of a new study suggest that patients living with HIV and one of a variety of potentially deadly cancers could be safely treated with the immunotherapy drug pembrolizumab, also known by its brand name, KEYTRUDA.
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A previously unknown autoimmune muscle disease involving sudden onset of debilitating muscle pain and weakness has been identified. The syndrome easily could be mistaken for other muscle diseases that require different treatment, so the findings are expected to help physicians…
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A study has revealed a close association between liposarcoma (LPS), a type of cancer that develops from fat cells, and the bromodomain and extraterminal (BET) protein family.
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An international team of researchers combined a calorie-restricted diet high in fat and low in carbohydrates with a tumor-inhibiting antibiotic and found the combination destroys cancer stem cells and mesenchymal cells, the two major cells found in glioblastoma, a fast-moving…
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New evidence shows that some cancer cells evade therapy by switching over to alternative molecular mechanisms that are not affected by existing anti-cancer treatments.
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A protein called PD-1, which is found on immune cells called CD8+ T cells, plays a key role in controlling infection with the Epstein-Barr virus, according to a study published May 30 in the open-access journal PLOS Pathogens by Christian…
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Intensive radiotherapy can be toxic in 60 percent of patients with tumors located in the gastrointestinal cavity. Increases in levels of the protein URI protect mice against high-dose ionizing radiation-induced gastrointestinal syndrome and enhance mouse intestinal regeneration and survival in…
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Researchers report on a potential therapeutic strategy to treat viral infection and boost immunity against cancer.
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Researchers have unveiled clues into how breast cancer cells spread around the body.
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Researchers have developed a simple new blood test that can detect the presence of seven different types of cancer by spotting unique patterns in the fragmentation of DNA shed from cancer cells and circulating in the bloodstream.
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In patients with chronic lymphocytic leukemia, the rate of disease growth is apt to follow one of three trajectories: relentlessly upward, steadily level, or something in between, scientists report in a new study.
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Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US every year. The study shows that MYC…
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Researchers describe how prostate cancer cells develop the ability to mimic bone-forming cells called osteoblasts, enabling them to proliferate in the bone microenvironment.
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A computer-assisted diagnostic procedure helps physicians detect the growth of low-grade brain tumors earlier and at smaller volumes than visual comparison alone, according to a new study. However, additional clinical studies are needed to determine whether early therapeutic interventions enabled…
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Common and rare SORLA single nucleotide polymorphisms have been associated with the development of Alzheimer's disease. So far, SORLA has been mainly studied in neurons, but the new study focused on SORLA's role in cancer cells.
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Unregulated cell division is a hallmark of cancer, and one of the key proteins involved in controlling cell division is called FoxM1. Abnormal activation of FoxM1 is a common feature of cancer cells and is correlated with poor prognosis, metastasis,…
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In a bid to reveal even more distinctive differences and similarities, researchers have developed two new artificial intelligence methods that decipher complex gene activity controlling cell fate decisions in retina development and relate this gene activity to what occurs in…
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Scientists have revealed the difference between a stem cell and other blood vessel cells using gene-sequencing technology.
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Researchers discover protein that protects parathyroid glands from excessive growth, suggesting potential drug-based strategies to treat hyperparathyroidism and other relevant tumors.
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Cancer therapies that use immune cells to trigger the body to attack tumors could be improved by a molecule that boosts their function, research suggests. Studies with mice have found the improved therapies produced a powerful anti-cancer immune response, which…
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