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New research has identified a new mechanism that plays a role in controlling how the herpes virus alternates between dormant and active stages of infection.
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Every year, more than 59,000 people around the world die of rabies and there remains no cheap and easy vaccine regimen to prevent the disease in humans. Now, researchers report that adding a specific immune molecule to a rabies vaccine…
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Researchers discovered a biological signature that could help identify which triple negative breast cancers might respond to immunotherapy and other treatments.
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Scientists have reported a new approach to treating lung cancer with inhaled nanoparticles.
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Researchers have developed a computational model, Combined Essentiality Scoring (CES), that enables accurate identification of essential genes in cancer cells for development of anti-cancer drugs.
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During spaceflight, astronauts experience similar physical stress as cancer patients undergoing treatments such as chemotherapy, immunotherapy, and targeted therapy. Researchers suggest that by mimicking a NASA astronaut's schedule of exercising before, during, and after a mission, cancer patients could reduce…
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Researchers have assessed Helicobacter pylori infection and gastric cancer risk in Americans, certain demographics and ethnic groups.
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The effectiveness of current treatments for melanoma, the deadliest form of skin cancer, could be improved by using approaches that wipe out the 'survival system' of cancer cells according to a new study. Researchers have demonstrated an approach, used in…
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Children who have received radiotherapy for a brain tumor can develop cognitive problems later in life. In their studies on mice, researchers have now shown that the drug lithium can help to reverse the damage caused long after it has…
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Scientists report the discovery of 'hyperhotspots' in the human genome, locations that are up to 170-times more sensitive to ultraviolet radiation (UV) from sunlight compared to the genome average.
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Chemo drugs are notoriously toxic, in part because so little of the drug actually gets to its target organ, requiring high doses. Scientists have now found a way to deliver nanoparticles filled with chemo to the lungs with 10x greater…
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A novel microfluidic device addresses one of the most costly steps in the engineered cell therapy manufacturing process, namely gene delivery. Deterministic mechanoporation, or DMP, uses fluid flow to pull each cell in a large population onto its own tiny…
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Medical researchers have discovered a new biomarker in cancer stem cells that govern cancer survival and spread, and it's raising hope that drug discovery to kill cancer stem cells could follow suit.
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Researchers have discovered that a leukemic cell is capable of transforming into a non-cancerous cell through epigenetic changes.
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A research team has found the mechanism that controls the growth of B1-cells in mice. The findings may lead to a deeper understanding of certain forms of cancer and autoimmune diseases.
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Scientists have used single-cell RNA analysis to find that supercentenarians -- meaning people over the age of 110 -- have an excess of a type of immune cell called cytotoxic CD4 T-cells.
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A transcription factor that aids neuron function also appears to enable a cell conversion in the prostate gland that can make an already recurrent cancer even more deadly, scientists say.
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A protein that drives growth of pancreatic cancer, and which could be a target for new treatments, has been identified.
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An international research effort has broken fresh ground in the race to find more effective treatments for the childhood cancer neuroblastoma, by uncovering a new and as-yet unexploited target in cancer cells that therapeutic drugs can be aimed at.
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Researchers have come up with a way to combine the anthrax toxin with a growth factor to kill bladder cancer cells and tumors.
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