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Biologic age, a DNA-based estimate of a person's age, is associated with future development of breast cancer, according to scientists. Biologic age was determined by measuring DNA methylation, a chemical modification to DNA that is part of the normal aging…
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Researchers are parsing how the retina hijacks an energy-producing chemical reaction to churn out molecular building blocks to renew photoreceptor membranes that keep our vision sharp.
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A new article outlines novel design guidance that could rapidly advance development of disease-sensing nanomaterials for use in new drug development.
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A new study suggests that high-fat diets fuel colorectal cancer growth by upsetting the balance of bile acids in the intestine and triggering a hormonal signal that lets potentially cancerous cells thrive. The findings could explain why colorectal cancer, which…
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In an effort to further individualize therapy and avoid over-treating patients, researchers report a new study using PET scans has identified a biomarker that may accurately predict which patients with one type of HER2-positive breast cancer might best benefit from…
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Previous studies have shown that estrogens and estrogen-like compounds reduce multiple sclerosis-like inflammation and disability in mice. At first glance these treatments appear promising, but they carry a host of negative side effects, from feminizing male mice to increasing the…
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Consumption of allium vegetables -- which include garlic, leeks, and onions -- was linked with a reduced risk of in colorectal cancer in a study of men and women in China.
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Spouses can help breast cancer patients with coping by positively reframing the cancer experience and other negative experiences. In general, positive reframing -- finding the silver lining -- was associated with less stress. Researchers suggest the findings can be extended…
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Researchers have published the first clinical study investigating the use of the direct oral anticoagulant, rivaroxaban, to prevent blood clots in patients with cancer at high-risk. The study found no significant reduction in venous thromboembolism or death in the overall…
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A clinical trial has found that patients responded to a new 'smart drug' for women with an aggressive form of breast cancer.
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Cancer patients who undergo chemotherapy could soon benefit from a new AI that is able to identify and predict the development of different combinations of symptoms -- helping to alleviate much of the distress caused by their occurrence and severity.
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An immunotherapeutic antibody therapy re-educates macrophages to activate passivated cytotoxic T cells to kill cancer. The antibody therapy prevented the growth of tumours in several mouse models. The development of the therapy has now progressed to patient testing in a…
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Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites. Researchers report that the heavy reliance of these tumors on a specific metabolic pathway presents a…
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In a strategic search, scientists created and screened a library of 45,000 new compounds containing chemical elements of widely used immune system suppressants, and say they found one that may prevent reperfusion injury, a tissue-damaging and common complication of surgery,…
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Scientists have discovered a compound that could be more effective in treating certain cancers than standard chemotherapy.
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Healthy T-cells play a crucial role in how the body fights follicular lymphoma, according to a new study. T-cells are a key part of the immune system and protect the body by fighting infections and cancer.
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Infections with a Human Papillomavirus (HPV) cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too. New research suggests…
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With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach their full potential, researchers need to optimize their various components.
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Study shows new forms of an older anti-cancer agent appear to enhance the immune system's ability to fight melanoma in mice.
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In a study of mice and human brain tumors researchers searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others. The results suggested that certain patients' tumor cells are less aggressive and…
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