Academic history

Jean-Yves Pierga, MD, PhD, practices as a Medical Oncologist at the Institut Curie, Paris Cancer Center, Paris, France. He has been a prominent figure in medical oncology since becoming a Professor of Medicine at Paris Descartes University, Paris, France, in 2005.

After earning a Silver Medal from Paris Medical School, Paris, France, Prof. Pierga completed his PhD at Paris University XI, Paris, France, where he investigated the detection and characterization of disseminated tumor cells in breast cancer. Following his fellowship at the Royal Marsden London, London, England, he previously led the Day-Clinic at the Institut Curie and has headed the research program on disseminated and circulating tumor cells since 2010. Prof. Pierga’s contributions to the field are reflected in over 120 peer-reviewed publications, and being an active member of several leading oncology societies, including the Société Française de Cancérologie (SFC), European Society for Medical Oncology (ESMO), and American Society of Clinical Oncology (ASCO).

Speaking on clinical trials in breast cancer

Prof. Jean-Yves Pierga’s research interests revolve around breast cancer treatment, reflected through his participation in innovative clinical trials and translational research. He has made significant contributions to the REALITY-01 clinical trial, which investigates the use of trastuzumab deruxtecan for patients with metastatic breast cancer. Prof. Pierga has also made significant strides in understanding the prognostic value of circulating tumor cells (CTCs) in metastatic breast cancer. He has focused on creating models that evaluate how the number of CTCs can forecast patient outcomes, offering crucial data that can enhance the design of clinical trials. His work in this field highlights his dedication to improving cancer therapies and advancing the field of precision oncology.