The neoHIP trial was presented as a trial in progress. So, this is a neoadjuvant study looking at paclitaxel with trastuzumab and pertuzumab plus or minus pembrolizumab. It’s an investigator initiated trial that’s supported by Merck, and the idea is that if you can synergize her two directed therapy with immune therapy, which has been done very successfully in the laboratory, if we can harness that synergy and administer drugs earlier on in the course of the disease, which has been an important lesson that we’ve learned from triple-negative breast cancer, the earlier on that you administer immune therapy, the more likely it is to be successful...
The neoHIP trial was presented as a trial in progress. So, this is a neoadjuvant study looking at paclitaxel with trastuzumab and pertuzumab plus or minus pembrolizumab. It’s an investigator initiated trial that’s supported by Merck, and the idea is that if you can synergize her two directed therapy with immune therapy, which has been done very successfully in the laboratory, if we can harness that synergy and administer drugs earlier on in the course of the disease, which has been an important lesson that we’ve learned from triple-negative breast cancer, the earlier on that you administer immune therapy, the more likely it is to be successful. So, that’s what this study is aimed to ask and answer. Can the addition of pembrolizumab improve pathologic complete response and allow for a backbone that includes only one chemotherapeutic?