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ESMO 2024 | DESTINY-Breast12: T-DXd in patients with HER2+/HR- breast cancer with brain metastasis

Giuseppe Viale, MD, FRCPath, University of Milan, Milan, Italy, highlights key findings from the Phase II DESTINY-Breast12 trial (NCT04739761). The trial confirmed the efficacy of trastuzumab deruxtecan (T-DXd) in patients with brain metastases from HER2-positive, hormone receptor-positive (HR+/HER2+) breast cancer. This trial thus solidified its role as an effective treatment option for these patients. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.

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