Nikhil Wagle, MD, Dana-Farber Cancer Institute, Boston, MA, discusses the development of resistance to endocrine therapies and CDK4/6 inhibitors in estrogen receptor-positive (ER+) metastatic breast cancer. Dr Wagle outlines work investigating mechanisms of resistance. This interview took place at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021.
Disclosures
Nikhil Wagle, MD, has participated in a consultancy/advisory role for Eli Lilly, has received grant support from Puma Biotechnologies, and has participated in a scientific advisory board for and is a stockholder of Relay Therapeutics.