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SABCS 2023 | Frequent intra-tumoral hypoxia in pregnancy-associated breast cancer

Pregnancy-Associated Breast Cancer (PABC) is breast cancer diagnosed during pregnancy or after childbirth. Carsten F.J Bakhuis, UMC Utrecht, Utrecht, Netherlands, notes that several interplaying mechanisms may promote tumor progression and adverse clinical outcomes in PABC. Utilizing a database of patients diagnosed with breast cancer during pregnancy in the Netherlands between 1988 and 2022, Dr Bakhuis reports that the presence of intra-tumoral hypoxia in PABC is common, with 78% of tumors expressing at least one of the studied hypoxia-associated proteins. This interview took place at the San Antonio Breast Cancer Symposium (SABCS) congress in San Antonio, TX.

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