ESMO 2022 | Updates from ADAURA: continued DFS benefit with osimertinib vs. placebo

Sanjay Popat, MBBS, FRCP, PhD, The Royal Marsden NHS Foundation Trust, London, UK, presents updated results from ADAURA (NCT02511106), a Phase III trial evaluating osimertinib, a third generation EGFR tyrosine kinase inhibitor, in patients with EGFR-mutant non-small cell lung cancer (NSCLC). With 2-years further follow-up, a continued disease-free survival (DFS) benefit was observed in the experimental arm which is consistent with the primary analysis and supports the use of osimertinib as standard of care for patients with EGFR-mutant stage IIB-IIIA NSCLC after complete tumor resection and adjuvant chemotherapy. This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.

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