Jeremie Calais, MD, UCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA, shares his views on whether fibroblast activated protein inhibitor (FAPI) PET/CT will replace F-fluorodeoxyglucose (FDG) PET/CT imaging in the next decade, and discusses the potential role of FAPI PET/CTs in therapeutics in the future. This interview took place at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021.