WCLC 2022 | Background of SANOVO trial for patients with advanced NSCLC

Qing Zhou, MD, PhD, Guangdong Lung Cancer Institute, Guangzhou, China, talks about the study design of the SANOVO trial (NCT05009836), a Phase III clinical study investigating the efficacy of osimertinib, combined with savolitinib or placebo, in patients with EGFRm+/MET+ non-small cell lung cancer (NSCLC). Dr Zhou discusses the background of savolitinib and its purpose in the study, alongside the primary endpoint of the trial, which was progression-free survival (PFS). She mentions other important secondary endpoints, such as the response rate, overall survival (OS) and safety of the trial. Dr Zhou hopes that results from this study will enable a new type of standard treatment for this specific population of NSCLC patients. This interview took place at the IASLC 2022 World Conference on Lung Cancer congress in Vienna, Austria.