Alexandre R. Zlotta, MD, PhD, Mount Sinai Hospital and University of Toronto, Toronto, Canada, discusses some of the key survivorship challenges facing patients with urothelial carcinoma, including the risks and benefits of bladder-sparing treatment compared to radical cystectomy. This interview took place at the American Society of Clinical Oncology (ASCO) Genitourinary Cancers Symposium 2022 in San Francisco, CA.