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GU Cancers 2021 | 18F-DCFPyL PET/CT imaging up-stages patients with prostate cancer

Frédéric Pouliot • 15 Feb 2021
GU Cancers 2021
Genitourinary Cancer Prostate Cancer
OSPREY

Frédéric Pouliot, MD, PhD, FRCSC, University Hospital of Quebec and Laval University, Quebec, Canada, outlines the results of the Phase II/III OSPREY trial (NCT02981368) investigating the prostate-specific membrane antigen (PSMA)-targeted agent, 18F-DCFPyL, with PET/CT imaging in patients with prostate cancer. Cohort A treated patients with newly-diagnosed prostate cancer and cohort B treated patients with recurrent or metastatic prostate cancer. 18F-DCFPyL PET/CT imaging upstaged 58% of patients from M0 to M1, of whom 91% who underwent extra-pelvic biopsy were confirmed to have M1 disease by pathology. This interview took place during the 2021 Genitourinary Cancers Symposium.

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