José María Oliver-Goldaracena, MD, Hospital Universitario La Paz, Madrid, Spain, talks on the use of ultrasound-guided cryoablation as a substitute for surgery in elderly patients with non resected breast cancer. This technique is well-tolerated, shows efficacy in the medium term, and may represent a less intensive alternative to surgery in elderly patients. This interview took place during the 17th St. Gallen International Breast Cancer Conference.