Nader Sanai, MD, Barrow Neurological Institute, Phoenix, AZ, discusses the limitations presented by tissue-based approaches to investigate glioblastoma. More pharmacokinetic and pharmacodynamic triggered approaches in Phase 0 trials and hybrid studies are being used to analyse drug effects in patients in real-time and derive conclusions. This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.
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