VJOncology is committed to improving our service to you

Share this video  

VJOncology is committed to improving our service to you

ASCO 2016 | Update on Study 19 trial of olaparib in serous ovarian cancer

Jonathan Ledermann, MD, FRCP from University College London, London, UK discusses his presentation on the update on the results of the Study 19 trial (NCT00753545). Study 19 was a randomized maintenance trial using olaparib in patients with recurrent high grade serous ovarian cancer, who had previously responded to platinum-based chemotherapy. Patients were randomized to olaparib or a placebo. Prof. Ledermann talks about the 3 year follow-up on overall survival (OS) and how there was meaningful improvement in patients taking olaparib. These findings, however, were not statistically significant. Prof. Ledermann further discusses how the trial looked into several supplementary exploratory endpoints to support the clinical value of the difference in OS of 4.7 months that was found. Endpoints looked at were: time to first subsequent treatment and time to second subsequent treatment. Prof. Ledermann discusses the importance of olaparib to OS rates. Recorded at the American Society of Oncology (ASCO) 2016 Annual Meeting held in Chicago, IL.

Sign-up for our Newsletter!

Keep up to date with all the latest news with our monthly newsletter