AACR 2023 | What are the potential applications of MYC inhibition in oncology?

Laura Soucek, PhD, Vall d’Hebron Institute of Oncology, Barcelona, Spain, discusses the future of OMO-103, a novel MYC inhibitor, and the potential indications it could be approved for. Whilst the drug can be used in all MYC-mutant tumors, pancreatic ductal adenocarcinoma (PADC) and non-small cell lung cancer (NSCLC) have been found to be particularly responsive to OMO-103. Combination therapies with chemotherapy or KRAS inhibitors in PADC and NSCLC respectively are additionally being assessed. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.

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