Felix Feng, MD, University of California San Francisco, San Francisco, CA, discusses the key areas of radiation oncology research in the field of genitourinary (GU) cancer. Prof. Fang highlights the performance of biomarkers, specifically the use of decipher in the RTOG-9601 study (NCT00002874) and the PAM50 classifier. This interview took place at the 2020 Genitourinary Cancers Symposium, held in San Francisco, CA.