Suneil Jain, MBBCh, PhD, Queen’s University Belfast, Belfast, UK, discusses the future of prostate cancer treatment at ASCO GU 2021, highlighting increased use and advances in stereotactic radiotherapy for localized prostate cancer, as well as developments in radiotherapy for advanced or localized metastatic prostate cancer. Prof. Jain also discusses the role of artificial intelligence (AI) in personalized prostate cancer treatment. This interview took place during the 2021 Genitourinary Cancers Symposium.