Ghassan Abou-Alfa, MD, Memorial Sloan-Kettering Cancer Center, New York City, NY, outlines novel targeted therapies in cholangiocarcinoma (CCA). Specifically discussed is results from the Phase III ClarIDHy study (NCT02989857), evaluating ivosidenib in IDH1-mutant, chemotherapy-refractory CCA. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).