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SABCS 2022 | TAKTIC: ipatasertib, endocrine therapy and CDK4/6i for patients with HR+/HER2- mBC

Seth Wander, MD, PhD, Massachusetts General Hospital, Boston, MA, discusses the results from the Phase I TAKTIC trial (NCT03959891) which evaluated combination therapy with the AKT inhibitor, ipatasertib, endocrine therapy and a CDK4/6 inhibitor for hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer (mBC). This combination approach was well tolerated in a heavily pre-treated population, with preliminary evidence of clinical efficacy. This interview took place at the San Antonio Breast Cancer Symposium (SABCS) 2022 in San Antonio, TX.

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