Martin Gore, PhD, FRCP, CBE from the Royal Marsden NHS Foundation, London, UK discusses the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) (NCT00058032) at the European Cancer Congress of the European Cancer Organisation (ECCO) 2017 in Amsterdam, Netherlands. UKCTOCS is a randomised control trial investigating the effect of screening on cancer mortality. It is a big achievement for the NHS, and will hopefully show promising results in terms of survival benefit in the long term. Dr Gore states that there has been a shift in focus from advanced disease to early disease, in the hopes of identifying a better biomarker to be used in population based screening. This should become more achievable as more data is collected.