Alastair Greystoke, MBChB, MSc, PhD, MRCP, Northern Institute for Cancer Research, Newcastle University, Newcastle, UK, discusses progressing frailty research in advanced lung cancer with reference to his research on the use of the Rockwood clinical frailty score. Patients who were recorded as frail were more likely to experience chemotherapy problems, dose reductions, or admittance to hospital for toxicity. This interview took place at the 18th British Thoracic Oncology Group (BTOG) 2020 congress held in Dublin, UK.