ESMO 2023 | Determinants of disease recurrence in non-metastatic, resected CRC

Julien Taieb, MD, PhD, Paris Descartes University, Paris, France, provides an overview of findings from an analysis of the prognostic value of KRAS and BRAF mutations in microsatellite-stable (MSS) and microsatellite instability-high (MSI-High) stage III colorectal cancer (CRC). The study, which molecularly profiled 8000 patients, revealed KRAS and BRAF mutations to be linked with increased recurrence. MSS colorectal cancer was additionally linked to higher rates of recurrence. This interview took place at the European Society for Medical Oncology (ESMO) 2023 Congress in Madrid, Spain.

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