Data from ERA 223 (NCT02043678) and many other uro-oncology trials were released at the European Society for Medical Oncology (ESMO) 2018 Congress, in Munich, Germany. We spoke to Alison Birtle, MD, of Royal Preston Hospital Lancashire Teaching Hospitals, Preston, UK, about this at the meeting. She highlights the learning points from ERA 223, which combined radium-223 and abiraterone, and discusses the upcoming data she is looking out for at ESMO 2018: pembrolizumab for BCG-refractory non-muscle invasive bladder cancer, the RANGE study of ramucirumab plus docetaxel for urothelial cancer (NCT02426125), and the STAMPEDE trial of systemic therapy for advancing or metastatic prostate cancer (NCT00268476).