Nadia Harbeck, MD, PhD, LMU Munich, Munich, Germany, discusses her highlights from the St. Gallen International Consensus Conference 2021, noting the benefits of the virtual format for both panelists and audience members in allowing lively global discussions. Prof. Harbeck goes on to share some of the most discussed topics at this year’s meeting, including the use of chemotherapy in early luminal breast cancer. This interview took place during the 17th St. Gallen International Breast Cancer Conference.