John Strickler, MD, Duke Cancer Center, Durham, NC, provides an overview of standard biomarker testing guidelines in the United States for colorectal cancer. Clinicians often look for KRAS, NRAS, BRAF and HER2 mutations and whilst HER2 mutations may not benefit from EFGR inhibitors, off-label HER2 inhibitors may benefit for patients with HER2 mutations. This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.
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