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AACR 2023 | The effect of futibatinib on hepatic impairment in ICC

Ling Gao, PhD, Taiho Oncology, Inc., Princeton, NJ, discusses findings from a study assessing the effect of futibatinib, an irreversible FGFR1-4 inhibitor, in livers of patients with advanced or metastatic intrahepatic cholangiocarcinoma (ICC) harboring FGFR2 gene fusions. Severity of hepatic impairment was not dependent of exposure to futibatinib, and dose adjustment is, thus, not necessary in patients. This interview took place at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Orlando, FL.

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