Jana McHugh, MD, of The Institute of Cancer Research, London, UK, discusses exciting new treatment options for prostate cancer, such as PARP inhibitors for patients with BRCA1 & 2 mutations and radionuclide therapy with prostate-specific membrane antigen (PSMA)-targeted radiation. Dr McHugh goes on to describe how the advent of hypofractionation is especially impactful during the COVID-19 pandemic as patients are likely to have less frequent hospital visits. This interview took place during the 2021 Genitourinary Cancers Symposium.