Kathrin Heinrich, MD, Ludwig-Maximilians-Universität München, Munich, Germany, emphasizes the significance impact of sex and gender on colorectal cancer management. While sex refers to biological differences, gender encompasses the social and cultural influences on disease development and treatment. These factors affect diagnostic accuracy, treatment efficacy, and side effect profiles. For example, female patients have a higher risk of severe adverse events with 5-fluorouracil treatment. Understanding how gender influences treatment response is critical for optimizing colorectal cancer care. This interview took place at the European Society for Medical Oncology (ESMO) 2024 Congress in Barcelona, Spain.
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