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ESMO 2026 | Promising early-phase trials exploiting MTAP deletion in mesothelioma

Paolo Bironzo, MD, PhD, University of Turin, Turin, Italy, comments on promising early-phase trial updates in mesothelioma. Exploiting MTAP deletions through PRMT5 and MTAP inhibitors have been touted as another future treatment avenue, with multiple trials currently exploring these agents in mesothelioma. This interview took place at the European Society for Medical Oncology (ESMO) 2026 Congress in Madrid, Spain.

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