ESMO 2022 | TILs prolong PFS compared with pembrolizumab in advanced melanoma

Sebastian Kobold, MD, PhD, Ludwig-Maximilians-Universität München, Munich, Germany, provides an overview of his highlight of the European Society for Medical Oncology (ESMO) 2022 Congress. Data was presented on the Phase III TIL (NCT02278887) trial, which compared tumor infiltrating lymphocytes (TIL) to standard ipilimumab in patients with metastatic melanoma. The trial met its primary endpoint of progression-free survival (PFS), demonstrating a median PFS of 7.2 months versus 3.1 months with the treatment of TILs versus pembrolizumab, respectively. This was the first clinical trial to show randomized efficacy of TILs in this patient population. This interview took place at the European Society for Medical Oncology (ESMO) 2022 Congress in Paris, France.

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