Benjamin Adam Weinberg, MD, Georgetown University, Washington, DC, describes the trial design and rationale of the Phase I PROTON-PANC trial (NCT03885284), which assessed proton radiation therapy in patients with pancreatic adenocarcinoma (PAC). 5 fractions of proton radiation therapy (PRT) were administered between cycles of adjuvant modified FOLFIRINOX. The radiation will aim to target local recurrence, which can negatively impact survival in patients. This interview took place at the American Society of Clinical Oncology (ASCO) 2023 Gastrointestinal Cancers (GI) Symposium in San Francisco, CA.
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