S. P. Somashekhar, MCh, FRCS.Ed, from the Manipal Comprehensive Cancer Center, India, provides us with an insight into the superior efficiency of the IBM Watson for Oncology (WFO) cognitive computing system in recommending treatment regimens for lung cancer and colorectal cancer, in comparison to a multimember multidisciplinary tumor board. This interview was filmed at the American Society of Oncology (ASCO) 2017 Annual Meeting in Chicago, IL.