Barbara Pistilli, MD, Institut Gustave Roussy, Villejuif, France, discusses the contradiction between the results of PALLAS (NCT02513394) and MONARCH-3 (NCT02246621) clinical trials. An explanation for the difference could be the more advanced stages of breast cancer involved in MONARCH-3. An analysis is still ongoing to clarify the contradiction in results. Dr Pistilli also discusses the promising results of the SOLAR-1 (NCT02437318) trial which has shown clinical significance. This interview was recorded via an online conference call with The Video Journal of Oncology (VJOncology).