Robert J. Jones, MD, PhD, University of Glasgow & Beatson West of Scotland Cancer Centre, Glasgow, UK, talks on highlights from the ASCO 2022 meeting in genitourinary (GU) cancer, particularly a trial investigating a IL-15 super agonist in combination with Bacillus Calmette-Guérin (BCG) in the BCG-refractory population of patients with high-risk non-muscle invasive bladder cancer. This interview took place at the American Society of Clinical Oncology (ASCO) 2022 Annual Meeting in Chicago, IL.