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ASCO 2024 | Personalizing chemotherapy in PDAC with AI-assisted transcriptomic signatures

Nelson Dusetti, PhD, Cancer Research Centre of Marseille, Marseille, France, provides an overview of the development of an artificial intelligence (AI)-assisted transcriptomic signature to personalize adjuvant chemotherapy in patients with resectable pancreatic ductal adenocarcinoma (PDAC). Due to the heterogenous nature of pancreatic cancer, the molecular characteristics are often not taken into account in decision making. The newly created transcriptomic signature will subsequently be validated in a cohort of patients randomized to receive either gemcitabine or FOLFIRINOX. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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Disclosures

Stock and Other Ownership Interests – Predicting Med
Patents, Royalties, Other Intellectual Property – PCT/EP2022/065222. Simple transcriptomic signatures to determine chemosensitivity for pancreatic ductal adenocarcinoma. SATT Sud-Est. Inventors: N. Dusetti, N. Fraunhoffer, J. Iovanna, 2021. Licensing to Predicting Med.