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GU Cancers 2025 | Promising biomarkers of response to immunotherapies in kidney cancer

Wenxin Xu, MD, Dana-Farber Cancer Institute, Boston, MA, comments on emerging biomarkers in kidney cancer, which remain an unmet need. PD-L1 expression has shown mixed results in previous trials, and transcriptomic signatures are being explored as potential predictors of response to immunotherapy versus anti-angiogenic therapies. This interview took place at the ASCO GU Cancers Symposium 2025 in San Francisco, CA.

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