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ASCO 2025 | Upcoming developments in kidney cancer treatment

David Braun, Yale University, New Haven, CT, comments on the upcoming developments in kidney cancer, particularly in the adjuvant setting with pembrolizumab, and the potential impact of novel agents such as savolitinib and belzutifan. He highlights the prospect of practice-changing studies and new agents that could transform treatment approaches in the coming years. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.

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Transcript

I think there’s a lot of exciting things to come within kidney cancer specifically. We’re going to have longer term follow up of some key data, pembrolizumab in the adjuvant setting. We’re going to hear about some novel agents as well, a newer TKI, savolitinib, a new update today that ARCC20, but also exciting data on new HIF-2 alpha inhibitors like belzutifan...

I think there’s a lot of exciting things to come within kidney cancer specifically. We’re going to have longer term follow up of some key data, pembrolizumab in the adjuvant setting. We’re going to hear about some novel agents as well, a newer TKI, savolitinib, a new update today that ARCC20, but also exciting data on new HIF-2 alpha inhibitors like belzutifan. So I think there’s going to be a wide range of both sort of updates of really practice changing studies, but also newer agents that’s hopefully going to change practice in the coming years.

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