Toni Choueiri, MD, Dana-Farber Cancer Institute, Boston, MA, discusses highlights from ESMO 2025 including the advancement of radioligand therapy in prostate cancer and major developments in bladder cancer, with positive trials in non-muscle invasive disease, frontline combinations, and ctDNA-based approaches that could change practice. In kidney cancer, attention is on the adjuvant RAMPART trial (NCT03288532) exploring dual CTLA-4 and PD-L1 inhibition, with preliminary but promising data, particularly in non-clear cell cohorts. This interview took place at the European Society for Medical Oncology (ESMO) 2025 Congress in Berlin, Germany.
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