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ESMO Asia 2025 | Advancements and regional trends in CAR-T cell therapy clinical trials

Han Chong Toh, MD, National Cancer Centre Singapore, Singapore, provides an overview of advancements in CAR-T cell therapy, highlighting that China is currently leading in the number of clinical trials, due to lower costs and regulatory flexibility. China’s approach to moving patients into first-in-human trials from animal studies is less stringent, but not less safe. This interview took place at 2025 European Society for Medical Oncology (ESMO) Asia Congress in Singapore, Singapore.

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